Protected Nucleosides
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
Quick view. We supply N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 67219-55-0. Catalog target purity: Specification on request.
Product profile
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is classified as nucleoside or protected nucleoside intermediate (Formula C37H35N3O7; molecular weight 633.69).
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine, reported solubility: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml. Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
- 5'-DIMETHOXYTRITYL-N4-BENZOYL-2'-DEOXYCYTIDINE
- 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-2'-DEOXYCYTIDINE
- 5'-O-DMT-N4-BZ-2'-DEOXYCYTIDINE
- BZ-DMT-DC
- BZ-DMT-DEOXYCYTIDINE
- DMT-DC-BZ
- DMT-N-BZ-DC
Useful catalog search terms
- CAS 67219-55-0
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| InChI | InChI=1S/C37H35N3O7/c1-44-29-17-13-27(14-18-29)37(26-11-7-4-8-12-26,28-15-19-30(45-2)20-16-28)46-24-32-31(41)23-34(47-32)40-22-21-33(39-36(40)43)38-35(42)25-9-5-3-6-10-25/h3-22,31-32,34,41H,23-24H2,1-2H3,(H,38,39,42,43)/t31-,32+,34+/m0/s |
|---|---|
| InChIKey | MYSNCIZBPUPZMQ-VOTWKOMSSA-N |
| SMILES | C(C1C=CC=CC=1)(C1C=CC(=CC=1)OC)(C1C=CC(=CC=1)OC)OC[C@@H]1[C@H](C[C@H](N2C=CC(=NC2=O)NC(C2C=CC=CC=2)=O)O1)O |
| Melting point | 119 °C |
| Boiling point | 668.71°C (rough estimate) |
| Density | 1.2234 (rough estimate) |
| pKa | 8.67±0.20(Predicted) |
| Form | powder to crystaline |
| Color | White to Almost white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
2'-O-TBDMS-rG(iBu)
Protected Nucleosides · CAS: 182007-86-9
BX-PN-00435'-O-DMTr-2'-O-TBDMS-rC(Ac)
Protected Nucleosides · CAS: 121058-85-3
BX-PN-00575'-O-TBDMS-3'-O-TBDMS-5-(hydroxymethyl)-dC
Protected Nucleosides · CAS: 1257247-39-4
BX-PN-00585'-O-TBDMS-3'-O-TBDMS-5-I-dC
Protected Nucleosides · CAS: 478843-96-8
BX-PN-00607'-O-TBDMS-4'-N-Trt-PMO-G(iBu)
Protected Nucleosides · CAS: N/A
BX-PN-00673'-O-TBDMS-2'-F-dG(iBu)
Protected Nucleosides · CAS: 2382967-92-0
Frequently asked questions
Can the package size for N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0262 and CAS 67219-55-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.