Modified Nucleosides
2',3'-Di-O-isopropylidene adenosine
Quick view. We supply 2',3'-Di-O-isopropylidene adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 362-75-4. Catalog target purity: Specification on request.
Product profile
2',3'-Di-O-isopropylidene adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C13H17N5O4; molecular weight 307.31).
2',3'-Di-O-isopropylidene adenosine — 2',3'-O-Isopropylideneadenosine is used as an organic chemical synthesis intermediate.
For 2',3'-Di-O-isopropylidene adenosine, reported solubility: Dioxane (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly). Storage: Store at RT.
Names and search terms
Confirmed or normalized name variants
- 2',3'-O-Isopropylideneadenosine
- 2',3'-IPA
- 2',3'-ISOPROPYLIDENEADENOSINE
- ISOPROPYLIDENE ADENOSINE
- Adenosine, 2',3'-O-(1-methylethylidene)-
- 2',3'-o-Isopropylideneadenosin
- 2',3'-O-Isopropylidene-D-adenosine
- 9-(2,3-O-Isopropylidene-beta-D-ribofuranosyl)adenine
Useful catalog search terms
- CAS 362-75-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C13H17N5O4/c1-13(2)21-8-6(3-19)20-12(9(8)22-13)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19H,3H2,1-2H3,(H2,14,15,16)/t6-,8-,9-,12-/m1/s |
|---|---|
| InChIKey | LCCLUOXEZAHUNS-WOUKDFQISA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@@H]2OC(O[C@H]12)(C)C |
| Melting point | 221-222 °C(lit.) |
| Boiling point | 447.81°C (rough estimate) |
| Density | 1.2370 (rough estimate) |
| pKa | 14.14±0.10(Predicted) |
| Form | Crystalline Powder |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2',3'-Di-O-isopropylidene adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2',3'-Di-O-isopropylidene adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0498 and CAS 362-75-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.