Halogenated Nucleosides
2',3'-Dideoxy-3'-fluorouridine
Quick view. A uridine analogue with the 2'-hydroxyl absent and fluorine at the 3' position, CAS 41107-56-6. CAS 41107-56-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Dideoxy-3'-fluorouridine is classified as 3'-fluoro dideoxy pyrimidine nucleoside (Formula C9H11FN2O4; molecular weight 230.19 g/mol).
2',3'-Dideoxy-3'-fluorouridine — A 3'-fluorinated dideoxyuridine intermediate for research in fluoronucleoside synthesis.
For 2',3'-Dideoxy-3'-fluorouridine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 3'-Fluoro-2',3'-dideoxyuridine
- 3'-F-ddU
- Uridine, 2',3'-dideoxy-3'-fluoro-
Useful catalog search terms
- 41107-56-6
- C9H11FN2O4
Physicochemical data
| InChIKey | BKIUEHLYJFLWPK-SHYZEUOFSA-N |
|---|---|
| Nucleobase | Uracil |
| Sugar modification | 2'-deoxy and 3'-fluoro |
| PubChem CID | 162450 |
| InChI | InChI=1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2',3'-Dideoxy-3'-fluorouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxy-3'-fluorouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0229 and CAS 41107-56-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.