Modified Nucleosides
2'-C-beta-Methylguanosine
Quick view. We supply 2'-C-beta-Methylguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 374750-30-8. Catalog target purity: Specification on request.
Product profile
2'-C-beta-Methylguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O5; molecular weight 297.27).
2'-C-beta-Methylguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-C-beta-Methylguanosine, reported solubility: H₂O: soluble at 5mg/mL, clear (warmed). Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C.
Names and search terms
Confirmed or normalized name variants
- 2'-C-Methylguanosine
- 2-C′-MeG
- -C-Methylguanosine
- Guanosine, 2'-C-methyl-
- 2'-C-Methylguanosine USP/EP/BP
Useful catalog search terms
- CAS 374750-30-8
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s |
|---|---|
| InChIKey | NVKAMPJSWMHVDK-GITKWUPZSA-N |
| SMILES | C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O)O |
| Boiling point | 733.1±70.0 °C(Predicted) |
| Density | 2.03 |
| pKa | 13.31±0.70(Predicted) |
| Form | powder |
| Color | white to beige |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-C-beta-Methylguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0504 and CAS 374750-30-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.