ddNTPs
3′-Azido-ddTTP Sodium Salt
Quick view. We supply 3′-Azido-ddTTP Sodium Salt as a 3'-azido dideoxy nucleotide analog for chain-termination, antiviral-mechanism and sequencing-method research. CAS 92586-35-1. Catalog target purity: ≥95%.
Product profile
3′-Azido-ddTTP Sodium Salt is classified as specialty research-use chemical building block (Formula C10H16N5O13P3·xLi; molecular weight 507.18 g/mol (calculated from molecular formula)).
3′-Azido-ddTTP Sodium Salt can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
For 3′-Azido-ddTTP Sodium Salt, reported solubility: Methanol (Slightly), Water (Slightly). Storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- Zidovudinetriphosphate
- zidovudine 5'-triphosphate
Useful catalog search terms
- CAS 92586-35-1
- Specialty research-use chemical building block
- azide click handle
- ddNTPs
Physicochemical data
| Key chemistry motifs | azide click handle |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Form | Sticky Solid |
| Color | Off-White |
| InChI | InChI=1S/C10H16N5O13P3/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h,6-8H,2,4H2,1H3,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)/t6-,7+,8+/m0/s |
| InChIKey | GLWHPRRGGYLLRV-XLPZGREQSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-] |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 3′-Azido-ddTTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3′-Azido-ddTTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DDNT-0008 and CAS 92586-35-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 3′-Azido-ddTTP Sodium Salt or the named structural feature represented by this product.