Halogenated Nucleosides
3'-Deoxy-3'-fluoro-xyloadenosine
Quick view. We supply 3'-Deoxy-3'-fluoro-xyloadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 20535-16-4. Catalog target purity: Specification on request.
Product profile
3'-Deoxy-3'-fluoro-xyloadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12FN5O3; molecular weight 269.24).
3'-Deoxy-3'-fluoro-xyloadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-Deoxy-3'-fluoro-xyloadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 9-(3-C-Fluoropentofuranosyl)-9H-purin-6-amine
- 9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine
- 9H-Purin-6-amine, 9-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-
- 3’-Deoxy-3’-fluoro-xyloadenosine, 9-(3-Deoxy-3-fluoro-beta-D-xylofuranosyl)adenine
- (2R,3S,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
Useful catalog search terms
- CAS 20535-16-4
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12FN5O4/c11-10(19)4(1-17)20-9(6(10)18)16-3-15-5-7(12)13-2-14-8(5)16/h2-4,6,9,17-19H,1H2,(H2,12,13,14)/t4-,6+,9-,10+/m1/s |
|---|---|
| InChIKey | HJQMFSDWWCLFTC-TWJUVVLDSA-N |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@]([C@H](O3)CO)(O)F)O)N |
| Boiling point | 628.6±65.0 °C(Predicted) |
| Density | 2.01±0.1 g/cm3(Predicted) |
| pKa | 12.45±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-xyloadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluoro-xyloadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0185 and CAS 20535-16-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.