Halogenated Nucleosides
3'-Deoxy-3'-fluorocytidine
Quick view. We supply 3'-Deoxy-3'-fluorocytidine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 123402-20-0. Catalog target purity: Specification on request.
Product profile
3'-Deoxy-3'-fluorocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H12FN3O4; molecular weight 245.21).
3'-Deoxy-3'-fluorocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-Deoxy-3'-fluorocytidine, storage: Sealed in dry,2-8°C.
Names and search terms
Confirmed or normalized name variants
- Cytidine, 3'-deoxy-3'-fluoro-
- 3'-F-3'-Dc
- 3'-Fluoro-3'-deoxycytidine
- 3'-Deoxy-3'-fluorocytidine, Antiviral agent
- 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Useful catalog search terms
- CAS 123402-20-0
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H12FN3O4/c10-6-4(3-14)17-8(7(6)15)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s |
|---|---|
| InChIKey | PKOBNLOZXOHYOP-XVFCMESISA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1F |
| Melting point | 221-223 °C |
| Boiling point | 500.1±60.0 °C(Predicted) |
| Density | 1.82±0.1 g/cm3(Predicted) |
| pKa | 12.81±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluorocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluorocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0165 and CAS 123402-20-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.