Amino-modified Nucleosides
3'-NH₂-ddA
Quick view. We supply 3'-NH₂-ddA as a 3'-amino dideoxyadenosine analog used in chain-termination, linker and enzymology research. CAS 7403-25-0. Catalog target purity: ≥99%.
Product profile
3'-NH₂-ddA is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O2; molecular weight 250.26).
3'-NH₂-ddA can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-NH₂-ddA, form: Powder.
Names and search terms
Confirmed or normalized name variants
- ((2S,3S,5R)
- 3'-AMINO-2'-DEOXY-D- ADENOSINE
- 3'-AMINO-2',3'-DIDEOXYADENOSINE
- 2',3'-dideoxy-3'-aminoadenosine
- 3'-AMINO-2',3'-DEOXY-D-ADENOSINE
- 3'-Amino-2',3'-dideoxy-D-adenosine
- -3-Amino-5-(6-amino-9H-purin-9-yl)
- Adenosine, 3'-amino-2',3'-dideoxy-
Useful catalog search terms
- CAS 7403-25-0
- Nucleoside or protected nucleoside intermediate
- Amino-modified Nucleosides
Physicochemical data
| Form | Powder |
|---|---|
| Color | Off-white to Yellow |
| InChI | InChI=1S/C10H14N6O2/c11-5-1-7(18-6(5)2-17)16-4-15-8-9(12)13-3-14-10(8)16/h3-7,17H,1-2,11H2,(H2,12,13,14)/t5-,6+,7+/m0/s |
| InChIKey | MVAJRASUDLEWKZ-RRKCRQDMSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 3'-NH₂-ddA or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-NH₂-ddA be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0006 and CAS 7403-25-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.