DMTr-protected Nucleosides
3'-O-DMTr-dA(Bz)
Quick view. We supply 3'-O-DMTr-dA(Bz) as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 140712-79-4. Catalog target purity: ≥95%.
Product profile
3'-O-DMTr-dA(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C38H35N5O6; molecular weight 657.71).
3'-O-DMTr-dA(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-DMTr-dA(Bz), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3-O-DMTr-N6-BENZOYL-DEOXY-ADENOSINE
- N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
- N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
- N6-BENZOYL-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
- N-Benzoyl-3'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxyadenosine
- 3'-O-DMT-dA(Bz)
Useful catalog search terms
- CAS 140712-79-4
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| Melting point | 125-126 °C |
| Density | 1.32±0.1 g/cm3(Predicted) |
| pKa | 14.44±0.10(Predicted) |
| InChI | InChI=1S/C38H35N5O6/c1-46-29-17-13-27(14-18-29)38(26-11-7-4-8-12-26,28-15-19-30(47-2)20-16-28)49-31-21-33(48-32(31)22-44)43-24-41-34-35(39-23-40-36(34)43)42-37(45)25-9-5-3-6-10-25/h3-20,23-24,31-33,44H,21-22H2,1-2H3,(H,39,40,42,45)/t31-,32+,33+/m0/s |
| InChIKey | LFXBQKFIXWICJR-WIHCDAFUSA-N |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)O[C@H]4C[C@@H](O[C@@H]4CO)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
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Frequently asked questions
Can the package size for 3'-O-DMTr-dA(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0020 and CAS 140712-79-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.