Protected Nucleosides
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
Quick view. An orthogonally protected 2'-deoxyadenosine bearing 3'-O-TBDMS and 5'-O-DMTr groups, identified by CAS 89947-86-4. CAS 89947-86-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is classified as protected nucleosides (Formula C37H45N5O5Si; molecular weight 667.87).
3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine — Orthogonally protected 2'-deoxyadenosine intermediate for further nucleoside and oligonucleotide building-block chemistry
For 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
- 3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine
Useful catalog search terms
- 3'-O-TBDMS-5'-O-DMTr-2'-deoxyadenosine
- CAS 89947-86-4
- CB33334257
Physicochemical data
| Nucleoside scaffold | beta-D-2'-Deoxyadenosine |
|---|---|
| 3' protection | O-TBDMS |
| 5' protection | O-DMTr |
| Adenine N6 | Unprotected amino group |
| Free ribose hydroxyls | None |
| PubChem CID | 11093601 |
| InChI | InChI=1S/C37H45N5O5Si/c1-36(2,3)48(6,7)47-30-21-32(42-24-41-33-34(38)39-23-40-35(33)42)46-31(30)22-45-37(25-11-9-8-10-12-25,26-13-17-28(43-4)18-14-26)27-15-19-29(44-5)20-16-27/h8-20,23-24,30-32H,21-22H2,1-7H3,(H2,38,39,40)/t30-,31+,32+/m0/s1 |
| InChIKey | BLILIIKIHHYPLG-DCMFLLSESA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C(N=CN=C65)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0304 and CAS 89947-86-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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