3'-O-TBDMS Phosphoramidites
3'-O-TBDMS-rA(Bz) Phosphoramidite
Quick view. We supply 3'-O-TBDMS-rA(Bz) Phosphoramidite as a 3'-O-TBDMS phosphoramidite for reversed or specialty RNA monomer synthesis. CAS 129451-75-8. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
3'-O-TBDMS-rA(Bz) Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C53H66N7O8PSi; molecular weight 988.19).
3'-O-TBDMS-rA(Bz) Phosphoramidite — N6-Benzoyl-3''-O-tert-butyldimethylsilyl-5''-O-DMT-adenosine 2''-CE phosphoramidite is a nucleotide and adenosine derivative used in the preparation of adenosine-inosine monophosphate (cAIMP) analogs that activate stimulator of interferon genes (STING).
For 3'-O-TBDMS-rA(Bz) Phosphoramidite, storage: 2-8°C. Form: Solid.
Names and search terms
Confirmed or normalized name variants
- 3'-TBDMS-Bz-rA Phosphoramidite
- 3'-TBDMS-rA(Bz) Phosphoramidite)
- DMT-3'-O-TBDMS-A(Bz)-CE-Phosphoramidite
- 3'-O-TBDMS-5'-O-DMT-N6-Bz-rA CED phosphoramidite
- 5'-O-DMT-3'-O-TBDMS-N6-Benzoyl-Adenosine 2'-CE phosphoramidite
- N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite
- N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CEphosphoramidite
Useful catalog search terms
- CAS 129451-75-8
- Protected oligonucleotide phosphoramidite building block
- TBDMS protection
- phosphoramidite coupling group
- 3'-O-TBDMS Phosphoramidites
Physicochemical data
| Key chemistry motifs | TBDMS protection; phosphoramidite coupling group |
|---|---|
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 3'-O-TBDMS-rA(Bz) Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
Frequently asked questions
Can the package size for 3'-O-TBDMS-rA(Bz) Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-3OTP-0001 and CAS 129451-75-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 3'-O-TBDMS Phosphoramidites product family and its named chemistry.