2'-FANA Nucleosides
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine
Quick view. We supply 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 69123-93-9. Catalog target purity: Specification on request.
Product profile
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11BrFN3O4; molecular weight 324.1).
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-Fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine
- 5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinocytidine
- 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-broMocytosine
- 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-bromocytosine
- 2(1H)-Pyrimidinone, 4-amino-5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
- 4-Amino-5-Bromo-1-(2-Deoxy-2-Fluoro-beta-D-Arabinofuranosyl)-2(1H)-Pyrimidinone
Useful catalog search terms
- CAS 69123-93-9
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| InChI | InChI=1S/C9H11BrFN3O4/c10-3-1-14(9(17)13-7(3)12)8-5(11)6(16)4(2-15)18-8/h,4-6,8,15-16H,2H2,(H2,12,13,17)/t4-,5+,6-,8-/m1/s |
| InChIKey | DPTQLSGNVUCAMZ-BYPJNBLXSA-N |
| SMILES | C1=C(C(=NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)N)Br |
| Boiling point | 513.3±60.0 °C(Predicted) |
| Density | 2.21±0.1 g/cm3(Predicted) |
| pKa | 12.84±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0072 and CAS 69123-93-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine or the named structural feature represented by this product.