Modified Nucleosides
5-Cyanouridine
Quick view. We supply 5-Cyanouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 4425-57-4. Catalog target purity: Specification on request.
Product profile
5-Cyanouridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H11N3O6; molecular weight 269.21).
5-Cyanouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Cyanouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Uridine, 5-cyano-
Useful catalog search terms
- CAS 4425-57-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H11N3O6/c11-1-4-2-13(10(18)12-8(4)17)9-7(16)6(15)5(3-14)19-9/h,5-7,9,14-16H,3H2,(H,12,17,18)/t5-,6-,7-,9-/m1/s |
|---|---|
| InChIKey | VIVLFSUDRCCWEF-JXOAFFINSA-N |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C#N |
| Melting point | 185 °C(Solv: ethanol (64-17-5)) |
| Density | 1.75±0.1 g/cm3(Predicted) |
| pKa | 7.10±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Cyanouridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Cyanouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0541 and CAS 4425-57-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.