Succinates
5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt
Quick view. We supply 5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt as a 2'-O-MOE guanosine succinate used to prepare nucleoside-loaded solid supports or terminally modified oligonucleotides. CAS 2622236-65-9. Catalog target purity: ≥98%.
Product profile
5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt is classified as oligonucleotide support or succinate intermediate.
5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 5'-DMT-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt
Useful catalog search terms
- CAS 2622236-65-9
- Oligonucleotide support or succinate intermediate
- DMTr/DMT protection
- 2'-O-MOE modification
- succinate linker
- Succinates
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; 2'-O-MOE modification; succinate linker |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-SUCC-0003DMTr-2'-F-dA(Bz)-3'-succinate, TEA salt
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
Succinates · CAS: N/A
BX-SUCC-0005DMTr-2'-F-dG(iBu)-3'-succinate, TEA salt
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BX-SUCC-0006DMTr-2'-F-dU-3'-succinate, TEA salt
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BX-SUCC-0007Reverse Abasic Succinate
Succinates · CAS: 401813-09-0
Frequently asked questions
Can the package size for 5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate,TEA salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0001 and CAS 2622236-65-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Succinates product family and its named chemistry.