dNTPs
5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt
Quick view. We supply 5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt as a 3'-O-azidomethyl reversible-terminator dNTP for controlled DNA polymerase extension and sequencing-chemistry development. CAS 1159990-37-0. Catalog target purity: Specification on request.
Product profile
5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt is classified as specialty research-use chemical building block (Formula C10H18N3O14P3; molecular weight 497.18).
5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
For 5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt, dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
Names and search terms
Confirmed or normalized name variants
- 3'-ONH2-dTTP Sodium Salt
- 3'-O-Aminothymidine-5'-triphosphate
- 3'-O-amino-Thymidine 5'-(tetrahydrogen triphosphate)
- Thymidine 5'-(tetrahydrogen triphosphate), 3'-O-amino-
Useful catalog search terms
- CAS 1159990-37-0
- Specialty research-use chemical building block
- azide click handle
- fluorescent label
- dNTPs
Physicochemical data
| Key chemistry motifs | azide click handle; fluorescent label |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Density | 1.90±0.1 g/cm3(Predicted) |
| pKa | 0.80±0.50(Predicted) |
| SMILES | C(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1ON |
| InChIKey | WTXJWVBIEUJGOO-XLPZGREQSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Fluorescent labels enable non-radioactive detection and can reduce downstream staining or secondary-label steps.
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe 5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DNTP-0046 and CAS 1159990-37-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-FAM-linker-PA-3'-O-azidomethyl-dGTP Sodium Salt or the named structural feature represented by this product.