Other Phosphoramidites
5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite)
Quick view. A protected 2'-O-MOE guanosine building block containing two phosphoramidite phosphorus centers, identified by supplier formula C55H78N8O12P2. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite) is classified as protected 2'-o-moe guanosine bis(phosphoramidite) (Formula C55H78N8O12P2; molecular weight 1105.22).
5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite) is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite), mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-2'-O-MOE-rG(iBu)-3'- ((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite
Useful catalog search terms
- C55H78N8O12P2
Physicochemical data
| CAS status | No public CAS assigned |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite) or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-OP-00045'-O-DMTr-2'-O-MOE-rT Bis(phosphoramidite)
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BX-OP-00065'-DMT Amino-Modifier C6 Phosphoramidite
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BX-OP-0007Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
Other Phosphoramidites · CAS: N/A
BX-OP-0008Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite
Other Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0003, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.