dNTPs
5-Propargylamino-dCTP
Quick view. A C5-propargylamino-modified dCTP for modified-nucleotide incorporation and two-step DNA labeling research. CAS 115899-39-3. Catalog target purity: 99.54%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Propargylamino-dCTP is classified as dntps (Formula C12H19N4O13P3 (free-acid basis); molecular weight 520.22 (free-acid basis)).
5-Propargylamino-dCTP — Modified dCTP incorporation research
For 5-Propargylamino-dCTP, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-Propargylamino-2'-deoxycytidine-5'-triphosphate
- Propargylamino-dCTP
- PA-dCTP
Useful catalog search terms
- 115899-39-3
Physicochemical data
| Parent InChIKey | LVTQIVFSMGDIPF-IVZWLZJFSA-N |
|---|---|
| Modification | C5 propargylamino handle on dCTP |
| Supply Form | Sodium-salt solid or aqueous solution; confirm counterion stoichiometry for requested material |
| Solid Form | White to off-white solid |
| Solution Form | Slightly yellow aqueous solution |
| Solution concentration | 100-110 mM; pH 7.5 +/-0.5 |
| Storage temperature | -20 C |
| PubChem CID | 11283796 |
| InChIKey | LVTQIVFSMGDIPF-IVZWLZJFSA-N |
| InChI | InChI=1S/C12H19N4O13P3/c13-3-1-2-7-5-16(12(18)15-11(7)14)10-4-8(17)9(27-10)6-26-31(22,23)29-32(24,25)28-30(19,20)21/h5,8-10,17H,3-4,6,13H2,(H,22,23)(H,24,25)(H2,14,15,18)(H2,19,20,21)/t8-,9+,10+/m0/s1 |
| SMILES | NCC#Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Two-step DNA labeling and amine-conjugation workflow development
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Propargylamino-dCTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Propargylamino-dCTP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0004 and CAS 115899-39-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.