dNTPs
5-Propargylamino-dUTP
Quick view. We supply 5-propargylamino-dUTP as a functionalized deoxyuridine triphosphate for enzymatic DNA labeling research. CAS 179101-49-6. Catalog target purity: ≥99%.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5-Propargylamino-dUTP is classified as specialty research-use chemical building block (Formula C12H18N3O14P3; molecular weight 521.2).
5-Propargylamino-dUTP — 5-(3-Amino-1-propyn-1-yl)-2''-deoxyuridine 5''-(Tetrahydrogen Triphosphate) is an intermediate in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma.
For 5-Propargylamino-dUTP, reported solubility: Water. Storage: Store sealed and dry; minimize repeated freeze-thaw cycles after reconstitution.
Names and search terms
Confirmed or normalized name variants
- 5-PA-dUTP
- 5-Propargylamino-2'-deoxyuridine-5'-triphosphate
- ap-dUTP
- ap-dUTP·3TEA
- 5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine
- 5-(3-Amino-1-propyn-1-yl)-2'-deoxyuridine 5'-triphosphate sodium salt
- Uridine 5'-(tetrahydrogen triphosphate),5-(3-amino-1-propynyl)-2'-deoxy-
- 5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate)
Useful catalog search terms
- CAS 179101-49-6
- Specialty research-use chemical building block
- alkyne click handle
- amine functionality
- dNTPs
Physicochemical data
| Key chemistry motifs | alkyne click handle; amine functionality |
|---|---|
| Purity basis | Research-grade target; the lot-specific CoA reports the release result and analytical method. |
| Functional group | Propargylamino |
| Supply form | Dry research material |
| Density | 1.95±0.1 g/cm3(Predicted) |
| pKa | 0.97±0.50(Predicted) |
| Form | Solid |
| Color | Yellow |
| SMILES | C(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C=C(C#CCN)C(=O)NC2=O)C[C@@H]1O |
| InChIKey | BGGIMXKBIBMKBL-IVZWLZJFSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Propargylamino-dUTP can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Propargylamino-dUTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Propargylamino-dUTP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0009 and CAS 179101-49-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-Propargylamino-dUTP or the named structural feature represented by this product.