Modified Nucleotides
6-Thio-GTP Sodium Salt
Quick view. We supply 6-Thio-GTP Sodium Salt as a sulfur-modified nucleotide analog for phosphorothioate, enzyme-mechanism and nuclease-resistance research. CAS 17670-19-8. Catalog target purity: Specification on request.
Product profile
6-Thio-GTP Sodium Salt is classified as nucleotide or nucleotide analog (Formula C10H16N5O13P3S; molecular weight 539.25).
6-Thio-GTP Sodium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 6-Thio-GTP Sodium Salt, reported solubility: Methanol (Slightly), Water (Slightly). Storage: -20°C, Hygroscopic.
Names and search terms
Confirmed or normalized name variants
- 6-Thio-GTP
- QENYANNAQSWPLM-DTUHVUQASA-N
- 6-Thioguanosine Triphosphate
- 6-thioguanosine 5'-triphosphate
- 6-Thioguanosine-5-O-triphosphate
- Guanosine 5'-(tetrahydrogen triphosphate), 6-thio-
Useful catalog search terms
- CAS 17670-19-8
- Nucleotide or nucleotide analog
- triphosphate group
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | triphosphate group |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Melting point | 102 - 104°C |
| Form | Solid |
| Color | Light Yellow |
| InChI | InChI=1S/C10H16N5O13P3S/c11-10-13-7-4(8(32)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-3,5-6,9,16-17H,1H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,32)/t3-,5-,6-,9+/m1/s |
| InChIKey | QENYANNAQSWPLM-BDXYJKHTSA-N |
| SMILES | N=c1nc(S)c2ncn([C@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
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Frequently asked questions
Can the package size for 6-Thio-GTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0084 and CAS 17670-19-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.