Cap Analogs
CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt
Quick view. We supply CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt as a trinucleotide cap analog for co-transcriptional mRNA capping and cap-structure research. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt is classified as rna cap analog or cap-related nucleotide.
CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- RNA cap analog or cap-related nucleotide
- 2'-O-methyl modification
- Cap Analogs
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA
Cap Analogs · CAS: 400806-46-4
BX-CA-0003CAP 4 m7G(UNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0004CAP 5 m7G(5')vppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 2645354-92-1
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0007CAP 9 m7G(2'F)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0002, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Cap Analogs product family and its named chemistry.