Modified Nucleotides
Carboxyaminoimidazole ribotide
Quick view. We supply Carboxyaminoimidazole ribotide as a base-modified nucleotide analog for studying how nucleobase substitution changes polymerase recognition, RNA/DNA stability and downstream biochemical behavior. CAS 6001-14-5. Catalog target purity: Specification on request.
Product profile
Carboxyaminoimidazole ribotide is classified as nucleotide or nucleotide analog (Formula C9H14N3O9P; molecular weight 339.2).
Carboxyaminoimidazole ribotide can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For Carboxyaminoimidazole ribotide, form: Solid.
Names and search terms
Confirmed or normalized name variants
- CAIR
- Carboxy-AIR
- 4-CARBOXY-5-AMINOIMIDAZOLE RIBOTIDE
- 5-Aminoimidazole-4-carboxylic acid ribonucleotide
- 5'-Phosphoribosyl-5-aminoimidazole-4-carboxylic acid
- 5-Aminoimidazole-4-carboxylic acid-1-b-D-ribofuranose 5'-monophosphate
- 5-amino-1-(5-O-phosphono-b-D-ribofuranosyl)-1H-Imidazole-4-carboxylicacid
- 1H-IMidazole-4-carboxylicacid, 5-aMino-1-(5-O-phosphono-b-D-ribofuranosyl)
Useful catalog search terms
- CAS 6001-14-5
- Nucleotide or nucleotide analog
- amine functionality
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Boiling point | 865.9±75.0 °C(Predicted) |
| Density | 2.30±0.1 g/cm3(Predicted) |
| pKa | 1.86±0.10(Predicted) |
| Form | Solid |
| Color | Off-white to light yellow |
| InChI | InChI=1S/C9H14N3O9P/c10-7-4(9(15)16)11-2-12(7)8-6(14)5(13)3(21-8)1-20-22(17,18)19/h2-3,5-6,8,13-14H,1,10H2,(H,15,16)(H2,17,18,19)/t3-,5-,6-,8-/m1/s |
| InChIKey | XFVULMDJZXYMSG-ZIYNGMLESA-N |
| SMILES | C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)N)C(=O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe Carboxyaminoimidazole ribotide or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: 78771-34-3
BX-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
BX-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
BX-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
BX-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
BX-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Frequently asked questions
Can the package size for Carboxyaminoimidazole ribotide be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0103 and CAS 6001-14-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.