DNA Phosphoramidites
DMTr-dT-3'-CE-Phosphoramidite
Quick view. We supply DMTr-dT-3'-CE-Phosphoramidite as a protected DNA CE phosphoramidite for routine and modified solid-phase oligonucleotide synthesis. CAS 98796-51-1. Catalog target purity: Specification on request.
Product profile
DMTr-dT-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C40H49N4O8P; molecular weight 744.81).
DMTr-dT-3'-CE-Phosphoramidite — 5''-O-[Bis(4-Methoxyphenyl)phenylmethyl]-thymidine 3''-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a nucleotide and reactant used in the solid-phase synthesis of phosphorothioate oligonucleotides, and in the synthesis of lipophilic 5''-phosphoramidate derivatives of DNA and RNA oligonucleotides.
For DMTr-dT-3'-CE-Phosphoramidite, reported solubility: soluble, clear. Storage: Sealed in dry,2-8°C.
Names and search terms
Confirmed or normalized name variants
- DMT-dT amidite
- DMT-dT Pharmadite
- DNAT-PHOSPHORAMIDITE
- T-CE phosphoramidite
- DT-CE PHOSPHORAMIDITE
- DMT-dT PhosphoraMidite
- DMT-dT-CE-Phosphoramidite
- DMT-DT AMIDITE 5G 6 PACK
Useful catalog search terms
- CAS 98796-51-1
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- phosphoramidite coupling group
- 2'-dT Phosphoramidite
- BX-DP-0013
- DNA Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; phosphoramidite coupling group |
|---|---|
| Density | 1.22 at 20℃ |
| Form | powder or granules |
| Color | white to off-white |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,38,r| |
| InChIKey | UNOTXUFIWPRZJX-DJKSPSSYNA-N |
| InChI | InChI=1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/m0/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- DMTr-dT-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
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BX-DP-0003DMTr-3'-dG(iBu)-2'-CE-Phosphoramidite
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BX-DP-0004DMTr-5-Me-dC(C6-O-Lev)-3'-CE-Phosphoramidite
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BX-DP-0005DMTr-5-[N-(naphthalen-2-ylmethyl)formamide]-dU-3'-CE-Phosphoramidite
DNA Phosphoramidites · CAS: 2133842-85-8
BX-DP-0006DMTr-dA(dmf)-3'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for DMTr-dT-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DP-0026 and CAS 98796-51-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry.