Halogenated Nucleosides
N1-(1,1,1-Trifluoroethyl)pseudouridine
Quick view. We supply N1-(1,1,1-Trifluoroethyl)pseudouridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 1613529-80-8. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
N1-(1,1,1-Trifluoroethyl)pseudouridine is classified as nucleoside or protected nucleoside intermediate (Formula C11H13F3N2O6; molecular weight 326.23).
N1-(1,1,1-Trifluoroethyl)pseudouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N1-(1,1,1-Trifluoroethyl)pseudouridine, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Useful catalog search terms
- CAS 1613529-80-8
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| Density | 1.649±0.06 g/cm3(Predicted) |
|---|---|
| pKa | 8.87±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N1-(1,1,1-Trifluoroethyl)pseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N1-(1,1,1-Trifluoroethyl)pseudouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0175 and CAS 1613529-80-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss N1-(1,1,1-Trifluoroethyl)pseudouridine or the named structural feature represented by this product.