Modified Nucleosides
N1-Methyladenosine
Quick view. We supply N1-Methyladenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 15763-06-1. Catalog target purity: ≥95%.
Product profile
N1-Methyladenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O4; molecular weight 281.27).
N1-Methyladenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N1-Methyladenosine, reported solubility: Soluble in water; confirm lot-specific concentration limits. Storage: −20 °C.
Names and search terms
Confirmed or normalized name variants
- 1-methyladenosine
- Adenosine, 1-methyl-
- 1-methyladenosine free base
- N,6-Didehydro-1,6-dihydro-1-methyladenosine
- (2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol
Useful catalog search terms
- CAS 15763-06-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| Melting point | 208–210 °C |
|---|---|
| SMILES | CN1C=NC2=C(C1=N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O |
| InChIKey | GFYLSDSUCHVORB-IOSLPCCCSA-N |
| InChI | InChI=1/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/s |
| Boiling point | 655.4±65.0 °C(Predicted) |
| Density | 1.88±0.1 g/cm3(Predicted) |
| pKa | 13.24±0.70(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N1-Methyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0742 and CAS 15763-06-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.