3'-O-Me Nucleosides
N7-Methyl-3'-O-methyl guanosine
Quick view. We supply N7-Methyl-3'-O-methyl guanosine as a 3'-O-methyl nucleoside for cap analog, modified RNA and protected nucleoside chemistry. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
N7-Methyl-3'-O-methyl guanosine is classified as nucleoside or protected nucleoside intermediate.
N7-Methyl-3'-O-methyl guanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N7-Methyl-3'-O-methyl guanosine, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Useful catalog search terms
- Nucleoside or protected nucleoside intermediate
- 3'-O-Me Nucleosides
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe N7-Methyl-3'-O-methyl guanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N7-Methyl-3'-O-methyl guanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-3OMN-0010, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 3'-O-Me Nucleosides product family and its named chemistry.