Amino-modified Nucleosides
7-Fluoro-7-deaza-2'-deoxyadenosine
Quick view. A 7-fluoro-7-deaza analogue of 2'-deoxyadenosine with a beta-D-erythro deoxyribofuranosyl configuration, identified by CAS 652965-07-6. CAS 652965-07-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
7-Fluoro-7-deaza-2'-deoxyadenosine is classified as amino-modified nucleosides (Formula C11H13FN4O3; molecular weight 268.25).
7-Fluoro-7-deaza-2'-deoxyadenosine — Reported as a precursor to a phosphoramidite used in the synthesis and 19F-NMR study of fluorinated oligonucleotides.
For 7-Fluoro-7-deaza-2'-deoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 7-Deaza-7-fluoro-2'-deoxyadenosine
Useful catalog search terms
- CAS 652965-07-6
Physicochemical data
| Systematic name | 7-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
|---|---|
| Sugar modification | 2'-deoxy |
| Base modification | 7-fluoro-7-deaza |
| PubChem CID | 9903477 |
| InChI | InChI=1S/C11H13FN4O3/c12-5-2-16(8-1-6(18)7(3-17)19-8)11-9(5)10(13)14-4-15-11/h2,4,6-8,17-18H,1,3H2,(H2,13,14,15)/t6-,7+,8+/m0/s1 |
| InChIKey | JAUILBSAMNYPFI-XLPZGREQSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C3=C(N=CN=C32)N)F)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 7-Fluoro-7-deaza-2'-deoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 7-Fluoro-7-deaza-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0225 and CAS 652965-07-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.