2'-O-Me Phosphoramidites
DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite
Quick view. A no-public-CAS 2'-O-methyl N4-acetylcytidine L-PSM phosphoramidite with formula C45H49N4O11PS. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite is classified as 2'-o-me phosphoramidites (Formula C45H49N4O11PS; molecular weight 884.94 g/mol).
DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMTr-2'-O-Me-N4-acetylcytidine-3'-(L)-PSM phosphoramidite
- BRP-00568
Useful catalog search terms
- AOAKYUMILRMJOU-KNYXQZDESA-N
Physicochemical data
| InChIKey | AOAKYUMILRMJOU-KNYXQZDESA-N |
|---|---|
| CAS status | No public CAS assigned in the reviewed exact source |
| Protected form | 5'-O-DMTr; 2'-O-Me; N4-acetyl; 3'-(L)-PSM |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0033, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.