2'-O-MOE Phosphoramidites
DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite is an N6-benzoyl-protected 2'-O-(2-methoxyethyl) adenosine building block for research-use oligonucleotide synthesis. CAS 251647-53-7. Catalog target purity: ≥98.0%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite is classified as protected 2'-o-moe adenosine phosphoramidite (Formula C50H58N7O9P; molecular weight 932.00).
DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite — N6-benzoyl-protected 2'-O-(2-methoxyethyl) adenosine phosphoramidite building block for research-use oligonucleotide synthesis.
For DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-O-MOE-A(Bz) Phosphoramidite
- DMT-2'-O-MOE-rA(Bz) Phosphoramidite
- N6-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)adenosine-3'-CE Phosphoramidite
Useful catalog search terms
- 251647-53-7
- PubChem 101234326
- C50H58N7O9P
Physicochemical data
| Base protection | N6-benzoyl |
|---|---|
| Ribose modification | 2'-O-(2-methoxyethyl) |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | VPBYBQBHLYRLHG-HDMAWCRFSA-N |
| InChI | InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-44-42(31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39)65-49(45(44)62-30-29-59-5)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC |
| PubChem CID | 101234326 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-2'-O-MOE-5-Me-rC(Ac)-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
BX-2OMP-0002DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: 2379296-21-4
BX-2OMP-0003DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
BX-2OMP-0004DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: 251647-56-0
BX-2OMP-0006DMTr-2'-O-MOE-rA(Bz)-3'-(1-hydroxy-N,N-diisopropyl)phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
BX-2OMP-0007DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0078 and CAS 251647-53-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.