2'-O-MOE Nucleosides
N1-Methyl-2'-O-(2-methoxyethyl)guanosine
Quick view. N1-Methyl-2'-O-(2-methoxyethyl)guanosine is listed for research-use inquiry under 2'-O-MOE Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N1-Methyl-2'-O-(2-methoxyethyl)guanosine is classified as 2'-o-moe nucleosides (Formula C14H21N5O6; molecular weight 355.35 g/mol).
N1-Methyl-2'-O-(2-methoxyethyl)guanosine is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For N1-Methyl-2'-O-(2-methoxyethyl)guanosine, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| InChIKey | DQOWQGVLFIABTG-QYVSTXNMSA-N |
| InChI | InChI=1S/C14H21N5O6/c1-18-12(22)8-11(17-14(18)15)19(6-16-8)13-10(24-4-3-23-2)9(21)7(5-20)25-13/h6-7,9-10,13,20-21H,3-5H2,1-2H3,(H2,15,17)/t7-,9-,10-,13-/m1/s1 |
| SMILES | CN1C(=O)C2=C(N=C1N)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OCCOC |
| Canonical SMILES | CN1C(=O)C2=C(N=C1N)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OCCOC |
| PubChem CID | 170902762 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe N1-Methyl-2'-O-(2-methoxyethyl)guanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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2'-O-MOE Nucleosides · CAS: 545374-76-3
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2'-O-MOE Nucleosides · CAS: 244105-55-3
BX-MN-01682'-O-(2-Methoxyethyl)guanosine
2'-O-MOE Nucleosides · CAS: 473278-54-5
BX-MN-01692'-O-(2-Methoxyethyl)adenosine
2'-O-MOE Nucleosides · CAS: 168427-74-5
BX-MN-01702'-O-(2-Methoxyethyl)cytidine
2'-O-MOE Nucleosides · CAS: 223777-16-0
BX-MN-01712'-O-(2-Methoxyethyl)uridine
2'-O-MOE Nucleosides · CAS: 223777-15-9
Frequently asked questions
Can the package size for N1-Methyl-2'-O-(2-methoxyethyl)guanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2MOE-0020, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.