Modified Nucleosides
2'-C-Methyl uridine
Quick view. We supply 2'-C-Methyl uridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 31448-54-1. Catalog target purity: Specification on request.
Product profile
2'-C-Methyl uridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O6; molecular weight 258.229).
2'-C-Methyl uridine — A 2’C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.
For 2'-C-Methyl uridine, storage: Sealed in dry,2-8°C. Form: powder to crystal.
Names and search terms
Confirmed or normalized name variants
- EOS-61181
- Uridine, 2'-C-Methyl-
- 2'-C-Methyluridine USP/EP/BP
- 2'-C-Methyl-1-β-D-ribofuranosyluracil
- 1-(2-C-Methyl-β-D-ribofuranosyl)uracil
- 1-(2-C-Methyl-beta-D-ribofuranosyl)uracil
- BX-MN-0320
Useful catalog search terms
- CAS 31448-54-1
- Nucleoside or protected nucleoside intermediate
- 2'-C-Methyluridine
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O6/c1-10(17)7(15)5(4-13)18-8(10)12-3-2-6(14)11-9(12)16/h2-3,5,7-8,13,15,17H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,10-/m1/s |
|---|---|
| InChIKey | NBKORJKMMVZAOZ-VPCXQMTMSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@](C)(O)[C@@H]1O |
| Melting point | 110-112 °C |
| Density | 1.572 |
| pKa | 9.39±0.10(Predicted) |
| Form | powder to crystal |
| Color | White to Almost white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2'-C-Methyl uridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-C-Methyl uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0480 and CAS 31448-54-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.