Halogenated Nucleosides
2'-Chloroadenosine
Quick view. We supply 2'-Chloroadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 146-77-0. Catalog target purity: Specification on request.
Product profile
2'-Chloroadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12ClN5O4; molecular weight 301.69).
2'-Chloroadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Chloroadenosine, reported solubility: H₂O: 10 mg/mL, clear, colorless. Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C.
Names and search terms
Confirmed or normalized name variants
- 2-CADO
- 2-CHLORO-D-ADENOSINE
- 2-CL-ADO
- 6-AMINO-2-CHLOROPURINE RIBOSIDE
- CHLOROADENOSINE
- 2-chloro-adenosin
- Cl AS
- Cl-Ado
Useful catalog search terms
- CAS 146-77-0
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s |
|---|---|
| InChIKey | BIXYYZIIJIXVFW-UUOKFMHZSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=C(Cl)N=3)N)N=C2)[C@H](O)[C@@H]1O |
| Melting point | 162 °C |
| Boiling point | 591.8±60.0 °C(Predicted) |
| Density | 1.8359 (rough estimate) |
| pKa | 13.05±0.70(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-Chloroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0036 and CAS 146-77-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.