Base-protected Nucleosides
2'-dC(Bz)
Quick view. We supply 2'-dC(Bz) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 4836-13-9. Catalog target purity: Specification on request.
Product profile
2'-dC(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C16H17N3O5; molecular weight 331.32).
2'-dC(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-dC(Bz), reported solubility: Soluble in methanol (50 mg/ml). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 4-(Benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)-2(1H)-pyrimidinone
- DC-BZ
- DC-N-BZ
- N4-BENZOYL-2'-DEOXYCYTIDINE
- N4-BZ-2'-DEOXYCYTIDINE
- n-benzoyl-2'-deoxy-cytidine
- NBZ-2'-DC
- N-BZ-DC
Useful catalog search terms
- CAS 4836-13-9
- Nucleoside or protected nucleoside intermediate
- Base-protected Nucleosides
Physicochemical data
| Melting point | 215-220 °C (dec.) |
|---|---|
| Density | 1.50±0.1 g/cm3(Predicted) |
| pKa | 8.67±0.20(Predicted) |
| InChIKey | MPSJHJFNKMUKCN-OUCADQQQSA-N |
| InChI | InChI=1S/C16H17N3O5/c20-9-12-11(21)8-14(24-12)19-7-6-13(18-16(19)23)17-15(22)10-4-2-1-3-5-10/h1-7,11-12,14,20-21H,8-9H2,(H,17,18,22,23)/t11-,12+,14+/m1/s |
| SMILES | C1[C@H]([C@@H](O[C@@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
2',3'-dideoxy-C(Ac)
Base-protected Nucleosides · CAS: 119818-52-9
BX-PN-00032',3'-dideoxy-C(Bz)
Base-protected Nucleosides · CAS: 120885-60-1
BX-PN-00052'-F-dG(DMF)
Base-protected Nucleosides · CAS: N/A
BX-PN-00062'-O-4'-C-Locked-5-Me-rC(Bz)
Base-protected Nucleosides · CAS: 206055-81-4
BX-PN-00072'-O-4'-C-Locked-rC(Bz)
Base-protected Nucleosides · CAS: 221229-74-9
BX-PN-00092'-O-4'-C-Locked-rG(iBu)
Base-protected Nucleosides · CAS: 206055-68-7
Frequently asked questions
Can the package size for 2'-dC(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0105 and CAS 4836-13-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry.