DNA Phosphoramidites
2'-dU Phosphoramidite
Quick view. We supply 2'-dU Phosphoramidite as a protected DNA CE phosphoramidite for routine and modified solid-phase oligonucleotide synthesis. CAS 109389-30-2. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-dU Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C39H47N4O8P; molecular weight 730.79).
2'-dU Phosphoramidite — Dmt-Du Amidite is used as a reactant in the synthesis of nucleotide related substances.
For 2'-dU Phosphoramidite, reported solubility: DMSO: 100 mg/mL (136.84 mM). Storage: 4°C, protect from light.
Names and search terms
Confirmed or normalized name variants
- dU Phosphoramidite
- 5'-DMT-dU phosphoramidite
- DMT-DURIDINE CYANOETHYL PHOSPHORAMIDITE)
- 5'-O-DMT- 2'-Deoxy Uridine Phosphoramidite
- 5'-O-DMT-2'-deoxyuridine-3'-CE-Phosphoramidite
- N-blocked-5'-O-DMT 3'-CED deoxyuridine phosphoramidite
- 2'-Deoxy-5'-O-(4,4-dimethoxytrityl) uridine-3'-CED phosphoramidite
- 5'-O-(4, 4'-Dimethoxytrityl)-2'-deoxyuridine-3'-CE-Phosphoramidite
Useful catalog search terms
- CAS 109389-30-2
- Protected oligonucleotide phosphoramidite building block
- phosphoramidite coupling group
- DNA Phosphoramidites
Physicochemical data
| Key chemistry motifs | phosphoramidite coupling group |
|---|---|
| Form | Solid |
| Color | White to off-white |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,37,r| |
| InChIKey | ZGJUDTLSWZPIDW-KLRJUOIRNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2'-dU Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
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BX-DP-0003DMTr-3'-dG(iBu)-2'-CE-Phosphoramidite
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BX-DP-0004DMTr-5-Me-dC(C6-O-Lev)-3'-CE-Phosphoramidite
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BX-DP-0005DMTr-5-[N-(naphthalen-2-ylmethyl)formamide]-dU-3'-CE-Phosphoramidite
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BX-DP-0006DMTr-dA(dmf)-3'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for 2'-dU Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DP-0016 and CAS 109389-30-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry.