TIPDS-protected Nucleosides
3',5'-O-TIPDS-2'-Spirocyclopropyl-U
Quick view. We supply 3',5'-O-TIPDS-2'-Spirocyclopropyl-U as a conformationally constrained uridine intermediate for modified nucleoside and sugar-conformation SAR. The TIPDS bridge protects 3'/5' hydroxyls while enabling 2'-position chemistry. CAS 140902-00-7. Catalog target purity: ≥95%.
Product profile
3',5'-O-TIPDS-2'-Spirocyclopropyl-U is classified as nucleoside or protected nucleoside intermediate.
3',5'-O-TIPDS-2'-Spirocyclopropyl-U can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3',5'-O-TIPDS-2'-Spirocyclopropyl-U, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- CAS 140902-00-7
- Nucleoside or protected nucleoside intermediate
- TIPDS protection
- TIPDS-protected Nucleosides
Physicochemical data
| Key chemistry motifs | TIPDS protection |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
Frequently asked questions
Can the package size for 3',5'-O-TIPDS-2'-Spirocyclopropyl-U be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0013 and CAS 140902-00-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the TIPDS-protected Nucleosides product family and its named chemistry.