Other Nucleosides
3'-O-azidomethylene-dC
Quick view. We supply 3'-O-azidomethylene-dC as a 3'-blocked deoxycytidine analog used in reversible-terminator chemistry. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
3'-O-azidomethylene-dC is classified as nucleoside or protected nucleoside intermediate.
3'-O-azidomethylene-dC can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-azidomethylene-dC, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Useful catalog search terms
- Nucleoside or protected nucleoside intermediate
- azide click handle
- Other Nucleosides
Physicochemical data
| Key chemistry motifs | azide click handle |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe 3'-O-azidomethylene-dC or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-O-azidomethylene-dA
Other Nucleosides · CAS: N/A
BX-NDO-00103'-O-azidomethylene-dG
Other Nucleosides · CAS: N/A
BX-NDO-00113'-O-azidomethylene-dT
Other Nucleosides · CAS: 136041-38-8
BX-NDO-00137-Deaza-2'-dG
Other Nucleosides · CAS: 86392-75-8
BX-NDO-0014Allopurinol riboside
Other Nucleosides · CAS: 16220-07-8
Frequently asked questions
Can the package size for 3'-O-azidomethylene-dC be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-NDO-0009, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 3'-O-azidomethylene-dC or the named structural feature represented by this product.