Reverse Phosphoramidites
3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite
Quick view. We supply 3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite as a reverse DNA guanosine amidite with DMF base protection for polarity-inverted DNA/oligonucleotide synthesis. CAS 261728-23-8. Catalog target purity: ≥98%.
Product profile
3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C43H53N8O7P; molecular weight 824.9).
3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite — 3'-DMTr-dG(dmf) is a guanosine derivative used in the synthesis of nucleic acids.
For 3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-DMT-2'-dG(dmf)-5'-CE-Phosphoramidite
- 3'-O-DMTr-2'-dG(dmf)-5'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- CAS 261728-23-8
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- phosphoramidite coupling group
- Reverse Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; phosphoramidite coupling group |
|---|---|
| Boiling point | 872.6±75.0 °C(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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BX-RP-00053'-O-DMTr-2'-O-MOE-rT-5'-CE-Phosphoramidite
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BX-RP-00063'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for 3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-RP-0007 and CAS 261728-23-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Reverse Phosphoramidites product family and its named chemistry.