Modified Nucleosides
5,6-Dihydrothymidine
Quick view. We supply 5,6-Dihydrothymidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5627-00-9. Catalog target purity: Specification on request.
Product profile
5,6-Dihydrothymidine is classified as nucleoside or protected nucleoside intermediate (Formula C10H16N2O5; molecular weight 244.24).
5,6-Dihydrothymidine — 5,6-Dihydrothymine is one of the most important products of base damage by gamma irradiation of DNA in anoxic conditions.
For 5,6-Dihydrothymidine, storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- Thymidine, 5,6-dihydro-
- (5S)-5,6-Dihydrothymidine
- 5,6-Dihydro-2'-deoxy-5-methyluridine
- 5,6-Dihydro thymidine,5,6-Dihydro-2’-deoxy-5-methyl uridine
- 1-[4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-methyl-1,3-diazinane-2,4-dione
- 1-[(2R,4S,5R)-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]-5-methyl-5,6-dihydrouracil
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione
Useful catalog search terms
- CAS 5627-00-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H16N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h5-8,13-14H,2-4H2,1H3,(H,11,15,16)/t5?,6-,7+,8+/m0/s |
|---|---|
| InChIKey | FEYHMSUYKIMUAL-UNYLCCJPSA-N |
| SMILES | CC1CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5,6-Dihydrothymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5,6-Dihydrothymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0586 and CAS 5627-00-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.