Halogenated Nucleosides
5-Bromo-2'-deoxyuridine
Quick view. We supply 5-Bromo-2'-deoxyuridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 59-14-3. Catalog target purity: Specification on request.
Product profile
5-Bromo-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C7H11BN2O7; molecular weight 245.98).
5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation.…
For 5-Bromo-2'-deoxyuridine, reported solubility: NH₄OH: 0.1 M at 20 °C, clear, colorless. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- bromodeoxyuridine
- 2'-DEOXY-5-BROMOROURIDINE
- 2'-DEOXY-5-BROMOURIDINE
- 5-BRDU
- 5-BROMO-1-(2-DEOXY-BETA-D-RIBOFURANOSYL)URACIL
- 5-BROMO-2'-DESOXYURIDINE
- 5-BROMO DEOXYURIDINE
- BDU
Useful catalog search terms
- CAS 59-14-3
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | 1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s |
|---|---|
| InChIKey | XMJRLEURHMTTRX-UHFFFAOYSA-N |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Br)C(=O)NC2=O |
| Melting point | 191-194 °C (dec.)(lit.) |
| Density | 1.8573 (rough estimate) |
| pKa | 7.73±0.10(Predicted) |
| Form | Crystals or Crystalline Powder |
| Color | White to yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Bromo-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Bromo-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0125 and CAS 59-14-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.