Halogenated Nucleosides
5'-Deoxy-5-fluorocytidine
Quick view. We supply 5'-Deoxy-5-fluorocytidine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 66335-38-4. Catalog target purity: Specification on request.
Product profile
5'-Deoxy-5-fluorocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H12FN3O4; molecular weight 245.21).
5'-Deoxy-5-fluorocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-Deoxy-5-fluorocytidine, reported solubility: DMSO (Slightly), Methanol (Slightly). Storage: Keep in dark place,Sealed in dry,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- 5-FLUORO-5'-DEOXYCYTIDINE
- 5'-DFCR
- 5'-Deoxy-5-fluoro-D-cytidine
- 5''-DEOXY-5-FLUOROCYTIDINE (5''-DFCR)
- 5-Fluoro-5’-deoxycytidine, 5’-DFCR
Useful catalog search terms
- CAS 66335-38-4
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H12FN3O4/c1-3-5(14)6(15)8(17-3)13-2-4(10)7(11)12-9(13)16/h2-3,5-6,8,14-15H,1H3,(H2,11,12,16)/t3-,5-,6-,8-/m1/s |
|---|---|
| InChIKey | YSNABXSEHNLERR-ZIYNGMLESA-N |
| SMILES | C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=NC2=O)N)F)O)O |
| Melting point | 196-198°C |
| Boiling point | 437.9±55.0 °C(Predicted) |
| Density | 1.84±0.1 g/cm3(Predicted) |
| pKa | 13.65±0.70(Predicted) |
| Form | Solid |
| Color | White to Light Beige |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5'-Deoxy-5-fluorocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-5-CF3-dU
Halogenated Nucleosides · CAS: 70-00-8
BX-HN-00026-Cl-purine-2'-deoxyriboside
Halogenated Nucleosides · CAS: 4594-45-0
BX-HN-00038-Cl-2'-dA
Halogenated Nucleosides · CAS: 85562-55-6
BX-HN-00042'-Chloro-2'-deoxycytidine
Halogenated Nucleosides · CAS: 10212-19-8
BX-HN-00055-bromo-2'-deoxycytidine
Halogenated Nucleosides · CAS: 1022-79-3
BX-HN-00065-Iodouridine
Halogenated Nucleosides · CAS: 1024-99-3
Frequently asked questions
Can the package size for 5'-Deoxy-5-fluorocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0248 and CAS 66335-38-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.