Modified Nucleosides
5-Methyl-2-thiouridine
Quick view. We supply 5-Methyl-2-thiouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 32738-09-3. Catalog target purity: Specification on request.
Product profile
5-Methyl-2-thiouridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O5S; molecular weight 274.29).
5-Methyl-2-thiouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Methyl-2-thiouridine, storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- m5s2U
- 2-Thioribothymine
- 2-thioribothymidine
- 2-Thioribosylthymine
- 2-THIOTHYMINE RIBOSIDE
- 2-Thio-5-methyluridine
- Uridine, 5-methyl-2-thio-
- RNA-modified nucleoside m5s2U
Useful catalog search terms
- CAS 32738-09-3
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O5S/c1-4-2-12(10(18)11-8(4)16)9-7(15)6(14)5(3-13)17-9/h,5-7,9,13-15H,3H2,1H3,(H,11,16,18)/t5-,6-,7-,9-/m1/s |
|---|---|
| InChIKey | SNNBPMAXGYBMHM-JXOAFFINSA-N |
| SMILES | CC1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| Melting point | 217 °C(Solv: ethanol (64-17-5)) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pKa | 7.18±0.23(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosylmethionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-0185(R-/S-) 5-Carbamoylhydroxy methyluridine
Modified Nucleosides · CAS: N/A
BX-MN-0186(R-/S-)5-(1-Hydroxy)(methoxycarbonyl)methyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0187(R-/S-)5-Carboxyhydroxymethyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0719(R)-N-(2,3-dihydro-1H-indenyl)adenosine
Modified Nucleosides · CAS: 96392-15-3
Frequently asked questions
Can the package size for 5-Methyl-2-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0482 and CAS 32738-09-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.