DMTr-protected Nucleosides
5'-O-DMTr-2'-dA(Bz)
Quick view. We supply 5'-O-DMTr-2'-dA(Bz) as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 64325-78-6. Catalog target purity: ≥95%.
Product profile
5'-O-DMTr-2'-dA(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C38H35N5O6; molecular weight 657.71).
5'-O-DMTr-2'-dA(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-2'-dA(Bz), reported solubility: DMSO (Slightly), Methanol (Slightly, Heated). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE
- 5'-O-DIMETHOXYTRITYL-N-BENZOYL DESOXYADENOSINE
- 5'-O-DMT-N6-BZ-2'-DEOXYADENOSINE
- BZ-DMT-DEOXYADENOSINE
- DMT-DA-BZ
- DMT-N-BZ-DA
- N6-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
- N(6)-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5'-O-(Dimethoxytrityl)-N-benzoyldeoxyadenosine
Useful catalog search terms
- CAS 64325-78-6
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| Melting point | 94 °C |
| Boiling point | 681.42°C (rough estimate) |
| Density | 1.2199 (rough estimate) |
| pKa | 7.87±0.43(Predicted) |
| Form | powder to crystal |
| Color | White to Almost white |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)NC(=O)C3=CC=CC=C3)N=C2)C[C@@H]1O |&1:25,27,47,r| |
| InChIKey | LPICNYATEWGYHI-RLHFKRISNA-N |
| InChI | InChI=1S/C38H35N5O6/c1-46-29-17-13-27(14-18-29)38(26-11-7-4-8-12-26,28-15-19-30(47-2)20-16-28)48-22-32-31(44)21-33(49-32)43-24-41-34-35(39-23-40-36(34)43)42-37(45)25-9-5-3-6-10-25/h3-20,23-24,31-33,44H,21-22H2,1-2H3,(H,39,40,42,45)/t31-,32+,33+/m0/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-dA(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0049 and CAS 64325-78-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.