Halogenated Nucleosides
5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine
Quick view. We supply 5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 134218-81-8. Catalog target purity: Specification on request.
Product profile
5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine is classified as nucleoside or protected nucleoside intermediate (Formula C15H25IN2O5Si; molecular weight 468.36).
5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine, storage: Keep in dark place,Inert atmosphere,Room temperature.
Names and search terms
Confirmed or normalized name variants
- 5'-O-(t-Butyldimethylsilyl)-5-iodo-2'-deoxyuridine
- 5′-O-TBSIODO DU
- 5'-O-TBS-5-iodo dU
- 5'-TBDMS-5-Iodo-2'-dU
- 5'-O-TBDMS-5-iodo-2'-deoxyuridine
- 2'-Deoxy-5'-O-TBDMS-5-Iodo-Uridine
- 5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodouridine
- 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYURIDINE
Useful catalog search terms
- CAS 134218-81-8
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C15H25IN2O5Si/c1-15(2,3)24(4,5)22-8-11-10(19)6-12(23-11)18-7-9(16)13(20)17-14(18)21/h7,10-12,19H,6,8H2,1-5H3,(H,17,20,21)/t10-,11+,12+/m0/s |
|---|---|
| InChIKey | OOAVDWDELLQGHO-QJPTWQEYSA-N |
| SMILES | CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)I)O |
| Melting point | 218-219 °C |
| Density | 1.52±0.1 g/cm3(Predicted) |
| pKa | 7.94±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodo-uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0027 and CAS 134218-81-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.