ddNTPs
5-Propargylamino-ddUTP
Quick view. We supply 5-propargylamino-ddUTP as a functionalized chain terminator for sequencing and polymerase research. CAS 114748-59-3. Catalog target purity: ≥95%.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5-Propargylamino-ddUTP is classified as specialty research-use chemical building block (Formula C12H18N3O13P3; molecular weight 505.20).
5-Propargylamino-ddUTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis.
For 5-Propargylamino-ddUTP, storage: Store sealed and dry; minimize repeated freeze-thaw cycles after reconstitution.
Names and search terms
Confirmed or normalized name variants
- 5-PA-ddUTP
- 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate
- 5-(3-AMINO-1-PROPYNYL)-2',3'-DIDEOXYURIDINE,5'-TRIPHOSPHATE
- 5-(3-Amino-1-propyn-1-yl)-2',3'-dideoxy-5'-(tetrahydrogen triphosphate)uridine
Useful catalog search terms
- CAS 114748-59-3
- Specialty research-use chemical building block
- alkyne click handle
- amine functionality
- ddNTPs
Physicochemical data
| Key chemistry motifs | alkyne click handle; amine functionality |
|---|---|
| Purity basis | Research-grade target; the lot-specific CoA reports the release result and analytical method. |
| Functional group | Propargylamino |
| Supply form | Dry research material |
| Density | 1.87±0.1 g/cm3(Predicted) |
| pKa | 0.80±0.50(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Propargylamino-ddUTP can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 5-Propargylamino-ddUTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-NH₂-ddATP Sodium Salt
ddNTPs · CAS: 90053-18-2
BX-DDNT-00023'-NH₂-ddCTP Sodium Salt
ddNTPs · CAS: 90053-17-1
BX-DDNT-00033'-NH₂-ddGTP Sodium Salt
ddNTPs · CAS: 90053-19-3
BX-DDNT-00043'-NH₂-ddTTP Sodium Salt
ddNTPs · CAS: 90053-16-0
BX-DDNT-00053′-Azido-ddATP Sodium Salt
ddNTPs · CAS: 92562-94-2
BX-DDNT-00063′-Azido-ddCTP Sodium Salt
ddNTPs · CAS: 92562-77-1
Frequently asked questions
Can the package size for 5-Propargylamino-ddUTP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0026 and CAS 114748-59-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-Propargylamino-ddUTP or the named structural feature represented by this product.