Halogenated Nucleosides
8-Bromoadenosine
Quick view. We supply 8-Bromoadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 2946-39-6. Catalog target purity: ≥98%.
Product profile
8-Bromoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12BrN5O4; molecular weight 346.14).
8-Bromoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Bromoadenosine, reported solubility: Soluble in DMSO and DMF; insoluble in water. Storage: −20 °C, protected from light.
Names and search terms
Confirmed or normalized name variants
- (2R,3R,4S,5R)-2-(6-AMINO-8-BROMO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
- 6-AMINO-8-BROMOPURINE RIBOSIDE
- 8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE
- 8-BROMO-D-ADENOSINE
- 6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside
Useful catalog search terms
- CAS 2946-39-6
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| Melting point | 210–212 °C (decomp.) |
|---|---|
| SMILES | C1=NC(=C2C(=N1)N(C(=N2)Br)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N |
| InChIKey | VJUPMOPLUQHMLE-UUOKFMHZSA-N |
| InChI | InChI=1S/C10H12BrN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s |
| Boiling point | 717.7±70.0 °C(Predicted) |
| Density | 1.8171 (rough estimate) |
| pKa | 12.89±0.70(Predicted) |
| Form | powder |
| Color | white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Bromoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0138 and CAS 2946-39-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.