Sulfurizing Reagents
DDTT Sulfurizing Reagent
Quick view. A dithiazole sulfur-transfer reagent used to form phosphorothioate internucleotide linkages during automated oligonucleotide synthesis. CAS 1192027-04-5. Catalog target purity: ≥95%.
Product profile
DDTT Sulfurizing Reagent is classified as oligonucleotide sulfur-transfer reagent (Formula C5H7N3S3; molecular weight 205.32).
DDTT Sulfurizing Reagent — Sulfurization of phosphite-triester linkages in phosphorothioate DNA and RNA synthesis.
For DDTT Sulfurizing Reagent, reported solubility: Methanol (Slightly, Sonicated), Water (Very Slightly, Heated, Sonicated). Storage: Sealed in dry,2-8°C.
Names and search terms
Confirmed or normalized name variants
- N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide
- N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)methanimidamide
- [(Dimethylamino-methylidene)amino]-3H-1,2,4-dithiazoline-3-thione
- (E)-N,N-dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide
- 3-((N,N-dimethylaminomethylidene)amino)-3H-1,2,4-dithiazole-5-thione
Useful catalog search terms
- CAS 1192027-04-5
- Oligonucleotide sulfur-transfer reagent
- Sulfurizing Reagents
Physicochemical data
| Melting point | 178-179 °C(Solv: 1,4-dioxane (123-91-1)) |
|---|---|
| Boiling point | 293.9±23.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| pKa | -0.21±0.20(Predicted) |
| Form | Solid |
| Color | Pale Yellow |
| SMILES | C(N(C)C)=NC1SSC(=S)N=1 |
| InChI | InChI=1S/C5H7N3S3/c1-8(2)3-6-4-7-5(9)11-10-4/h3H,1-2H3 |
| InChIKey | YRDSDHFBUHFDPG-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Cycle-development studies comparing sulfur-transfer rate and synthesis-platform compatibility.
Related products
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BX-SR-0005Tetraethylthiuram Disulfide (TETD)
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BX-SR-00063-Ethoxy-1,2,4-dithiazoline-5-one (EDITH)
Sulfurizing Reagents · CAS: N/A
BX-SR-0007Dimethylthiuram Disulfide (DTD)
Sulfurizing Reagents · CAS: 2438-90-6
Frequently asked questions
Can the package size for DDTT Sulfurizing Reagent be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SR-0001 and CAS 1192027-04-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Sulfurizing Reagents product family and its named chemistry.