RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite as a standard guanosine monomer for RNA synthesis. CAS 147201-04-5. Catalog target purity: Specification on request.
Product profile
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C50H68N7O9PSi; molecular weight 970.18).
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite — 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is mainly used as a biochemical reagent.
For DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite, storage: Sealed in dry,Store in freezer, under -20°C. Form: powder.
Names and search terms
Confirmed or normalized name variants
- i-bu-rG Phosphoramidite
- 2’-TBDMS-rG(N-ibu)Phosphoramidite
- 2'-TBDMS-ibu-G-CE-Phosphoramidite
- 5'-O-DMT-2'-TBDMS-rG(N-iBu)-3'-CEDPA
- DMT-2′O-TBDMS-rG(ib) Phosphoramidite
- 5'-DMT-2'-TBDMS-N2-ibu-rG phosphoramidite
- REF DUPL: 2'-TBDMS-rG(N-ibu)Phosphoramidite
- 5'-O-DMT- 2'-O-TBDMS- N2-Isobutyryl-Guanosine Phosphoramidite
Useful catalog search terms
- CAS 147201-04-5
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- 2'-O-TBDMS-rG(ibu) Phosphoramidite
- BX-R2OT-0012
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
|---|---|
| Form | powder |
| Color | white to off-white |
| SMILES | COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(NC(=O)C(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6 |
| InChIKey | PGJKESPHANLWME-FTZVBZPOSA-N |
| InChI | InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0024 and CAS 147201-04-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.