Other Phosphoramidites
N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite
Quick view. We supply N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite as a hydrophobic or alkyl-modified phosphoramidite for installing lipophilic side chains into oligonucleotides. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite, affinity tags can introduce steric effects; spacer length, label position and enzymatic incorporation efficiency should be verified.
Names and search terms
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- amine functionality
- biotin affinity tag
- phosphoramidite coupling group
- Other Phosphoramidites
Physicochemical data
| Key chemistry motifs | amine functionality; biotin affinity tag; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- Biotin and hapten labels provide strong downstream detection or enrichment options without radioactive labeling.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Affinity tags can introduce steric effects; spacer length, label position and enzymatic incorporation efficiency should be verified.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0137, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss N1-(4, 4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N, N-diisopropyl)-phosphoramidite or the named structural feature represented by this product.