Modified Nucleosides
N6-Ethyl-2'-O-methyladenosine
Quick view. An adenosine building block bearing N6-ethyl and 2'-O-methyl modifications for structure-specific nucleoside and nucleotide research. CAS 157309-11-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Ethyl-2'-O-methyladenosine is classified as modified nucleosides (Formula C13H19N5O4; molecular weight 309.32).
N6-Ethyl-2'-O-methyladenosine — N6-ethyl- and 2'-O-methyl-modified adenosine building block for structure-specific nucleoside and nucleotide research.
For N6-Ethyl-2'-O-methyladenosine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- CAS 157309-11-0
- PubChem CID 57009522
Physicochemical data
| PubChem CID | 57009522 |
|---|---|
| InChIKey | KEZGDNKRYXLGKM-QYVSTXNMSA-N |
| IUPAC name | (2R,3R,4R,5R)-5-[6-(ethylamino)purin-9-yl]-2-(hydroxymethyl)-4-methoxyoxolan-3-ol |
| SMILES | CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OC |
| Nucleobase modification | N6-ethyl |
| Sugar modification | 2'-O-methyl |
| InChI | InChI=1S/C13H19N5O4/c1-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(21-2)9(20)7(4-19)22-13/h5-7,9-10,13,19-20H,3-4H2,1-2H3,(H,14,15,16)/t7-,9-,10-,13-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe N6-Ethyl-2'-O-methyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N6-Ethyl-2'-O-methyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0785 and CAS 157309-11-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.