Nucleosides & Deoxynucleosides
rG
Quick view. rG (guanosine) is a natural ribonucleoside for nucleotide synthesis, RNA chemistry and biochemical reference use. CAS 118-00-3. Catalog target purity: ≥99%.

Product profile
rG is classified as nucleoside or protected nucleoside intermediate (Formula C10H13N5O5; molecular weight 283.24).
rG can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For rG, reported solubility: 0.1 M NaOH: 0.1 g/mL, clear, slightly yellow. Storage: Store at RT.
Names and search terms
Confirmed or normalized name variants
- 2-AMINO-9-BETA-D-RIBOFURANOSYL-9H-PURINE-6-(1H)-ONE
- 9-B-D-RIBOFURANOSYLGUANINE
- 9-[BETA-D-RIBOFURANOSYL]GUANINE
- D-GUANOSINE
- GR
- GUANINE-9-BETA-D-RIBOFURANOSIDE
- GUANINE RIBOSIDE
- GUANOSINE
Useful catalog search terms
- CAS 118-00-3
- Nucleoside or protected nucleoside intermediate
- Nucleosides & Deoxynucleosides
Physicochemical data
| Melting point | 250 °C (dec.) (lit.) |
|---|---|
| Boiling point | 425.8°C (rough estimate) |
| Density | 1.3790 (rough estimate) |
| pKa | pK1:1.9(+1);pK2:9.25(0);pK3:12.33(OH) (25°C) |
| Form | Powder |
| Color | White to light yellow |
| SMILES | [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1 |
| InChI | 1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s |
| InChIKey | NYHBQMYGNKIUIF-UUOKFMHZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
2'-dA
Nucleosides & Deoxynucleosides · CAS: 958-09-8
BX-NDO-00022'-dA·H₂O
Nucleosides & Deoxynucleosides · CAS: 16373-93-6
BX-NDO-00032'-dC
Nucleosides & Deoxynucleosides · CAS: 951-77-9
BX-NDO-00042'-dG
Nucleosides & Deoxynucleosides · CAS: 961-07-9
BX-NDO-00052'-dG·H₂O
Nucleosides & Deoxynucleosides · CAS: 312693-72-4
BX-NDO-00062'-dT
Nucleosides & Deoxynucleosides · CAS: 50-89-5
Frequently asked questions
Can the package size for rG be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-NDO-0020 and CAS 118-00-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Nucleosides & Deoxynucleosides product family and its named chemistry.
