Amino-modified Nucleosides
2'-Deoxy-8-methylamino-adenosine
Quick view. We supply 2'-Deoxy-8-methylamino-adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 13389-10-1. Catalog target purity: Specification on request.
Product profile
2'-Deoxy-8-methylamino-adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H16N6O3; molecular weight 280.28).
2'-Deoxy-8-methylamino-adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Deoxy-8-methylamino-adenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 9-(2-deoxypentofuranosyl)-n8-methyl-9h-purine-6,8-diamine
Useful catalog search terms
- CAS 13389-10-1
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C11H16N6O3/c1-13-11-16-8-9(12)14-4-15-10(8)17(11)7-2-5(19)6(3-18)20-7/h4-7,18-19H,2-3H2,1H3,(H,13,16)(H2,12,14,15) |
| InChIKey | QPKHFQHVYJMSQB-UHFFFAOYSA-N |
| SMILES | CN=c1[nH]c2c(N)ncnc2n1C1CC(O)C(CO)O1 |
| Boiling point | 634.5±65.0 °C(Predicted) |
| Density | 1.85±0.1 g/cm3(Predicted) |
| pKa | 13.78±0.60(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Deoxy-8-methylamino-adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Deoxy-8-methylamino-adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0018 and CAS 13389-10-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.